Invitrogen™ Phospho-Nudel (Thr219) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106190

Catalog No. PIPA5106190

Description

Antibody detects endogenous levels of NDEL1 only when phosphorylated at Thr219.

This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: Phospho-Nudel (Thr219)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ndel1
• Gene Alias: 2600006O07Rik; ATP-sensitive inward rectifier potassium channel 15; DKFZp451M0318; endooligopeptidase A; EOPA; Inward rectifier K(+) channel Kir4.2; Kcnj15; Kir4.2; LIS1-interacting protein NUDEL; LIS1-interacting protein NUDEL; endooligopeptidase A; MITAP1; Mitosin-associated protein 1; mitosin-associated protein MITAP1; mNudel; mNudE-L; NDE1L1; NDE2; Ndel1; nuclear disribution gene E like; nuclear distribution gene E-like homolog 1; nuclear distribution gene E-like homolog 1 (A. nidulans); nuclear distribution protein nudE-like 1; nudE neurodevelopment protein 1 like 1; nudE neurodevelopment protein 1-like 1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog like 1; nudE nuclear distribution gene E homolog-like 1; Nude2; NUDEL; NUDE-like protein; Potassium channel, inwardly rectifying subfamily J member 15; potassium channel, inwardly rectifying subfamily J, member 15; potassium inwardly-rectifying channel, subfamily J, member 15; Protein mNudE-like; Protein Nudel; unnamed protein product
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170845, 81565, 83431
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q78PB6, Q9ERR1, Q9GZM8
• Gene Symbols: Ndel1
• Immunogen: A synthesized peptide derived from human NDEL1(Accession Q9GZM8), corresponding to amino acid residues around phosphorylated Thr219.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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