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Invitrogen™ Phospho-OLIG2 (Ser10, Ser13, Ser14) Polyclonal Antibody
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Catalog No. PIPA535405
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PIPA535405 100 μL
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Catalog No. PIPA535405 Supplier Invitrogen™ Supplier No. PA535405
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with guinea pig, mouse, human, non-human primate and zebrafish based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-OLIG2 (Ser10, Ser13, Ser14)
Applications Western Blot
Classification Polyclonal
Concentration ∼0.25 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.1 mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene OLIG2
Gene Accession No. Q13516, Q9EQW6
Gene Alias AI604895; basic domain, helix-loop-helix protein, class B, 1; Basic helix loop helix protein class B1 (bHLHB1); basic helix-loop-helix protein 19 (bHLHe19); bHLH transcription factor; BHLHB1; bHLHe19; Class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; Olg-2; OLIG2; olig-2; Oligo2; Oligo2 antibody; oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; oligodendrocyte transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; Protein kinase C-binding protein 2; Protein kinase C-binding protein 2 (PRKCBP2); Protein kinase C-binding protein RACK17; RACK17; RK17; wu:fc64g09
Gene Symbols OLIG2
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser10,13,14 of human Olig2 conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10215, 304103, 50913
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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