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Invitrogen™ Phospho-OPRK1 (Ser369) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA540216
Description
Phospho-OPRK1 (Ser369) Polyclonal Antibody for Western Blot, IHC, ELISA
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Specifications
Phospho-OPRK1 (Ser369) | |
Polyclonal | |
Unconjugated | |
OPRK1 | |
kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; OPRK1; Oprk2; Ork1; R21; Ror-d | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
18387, 29335 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry, Western Blot | |
1 mg/mL | |
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P33534, P34975 | |
OPRK1 | |
Synthesized peptide derived from mouse KOR-1 around the phosphorylation site of S369. | |
100 μL | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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