Invitrogen™ Phospho-OPRM1 (Ser377) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105163

Catalog No. PIPA5105163

Description

Antibody detects endogenous levels of OPRM1 only when phosphorylated at Ser377, which site historically referenced as Ser375.

The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

Specifications

• Antigen: Phospho-OPRM1 (Ser377)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OPRM1
• Gene Alias: hMOP; KIAA0403; LMOR; MOP; MOP receptor; MOP-R; Mor; MOR1; M-OR-1; MOR-1; MOR-1C; MOR-1O; MORA; Mu opiate receptor; mu opioid receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant mMOR-1Z; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; mu-opioid receptor; muOR; MUOR1; mu-type opioid receptor; Opioid mu receptor; Opioid Receptor; opioid receptor B; opioid receptor mu 1; opioid receptor, mu 1; OPRM; Oprm1; Oprrm1; OTTHUMP00000017463; Ror-b
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18390, 4988
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P35372, P42866
• Gene Symbols: OPRM1
• Immunogen: A synthesized peptide derived from human OPRM1(Accession P35372), corresponding to amino acid residues around phosphorylated Ser377.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG