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Invitrogen™ Phospho-Oxytocin Receptor (Thr235) Polyclonal Antibody
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Catalog No. PIPA5105111
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PIPA5105111 100 μL
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Catalog No. PIPA5105111 Supplier Invitrogen™ Supplier No. PA5105111
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Oxytocin Receptor only when phosphorylated at Thr235.

The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor is made up of 389 amino acids and has a molecular weight of ~43,000 kDa. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium or the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors, including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.
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Specifications

Antigen Phospho-Oxytocin Receptor (Thr235)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Oxtr
Gene Accession No. P30559, P70536, P97926
Gene Alias Otr; OT-R; OTR1; oxcytocin receptor; OXTR; Oxt-r; Oxytocin receptor
Gene Symbols Oxtr
Host Species Rabbit
Immunogen A synthesized peptide derived from human OXTR(Accession P30559), corresponding to amino acid residues around phosphorylated Thr235.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18430, 25342, 5021
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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