Invitrogen™ Phospho-p300 (Ser1834) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564531

Catalog No. PIPA564531

Description

Phospho-p300 (Ser1834) Polyclonal Antibody detects endogenous levels of p300 only when phosphorylated at Ser1834.

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

Specifications

• Antigen: Phospho-p300 (Ser1834)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EP300
• Gene Alias: A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; Ep300; Histone acetyltransferase p300; Histone butyryltransferase p300; Histone crotonyltransferase p300; KAT3B; P300; p300 HAT; Protein propionyltransferase p300; RSTS2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170915, 2033, 328572
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: B2RWS6, Q09472
• Gene Symbols: EP300
• Immunogen: A synthesized peptide derived from human E1A-associated Protein p300 (Phospho-Ser1834).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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