Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Phospho-p38 MAPK (Thr179, Tyr181) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538416

Catalog No. PIPA538416


Description

Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-p38 MAPK (Thr179, Tyr181)
Polyclonal
Unconjugated
MAPK14
CRK1, CSAID binding protein, CSBP, CSBP1, CSBP2, Cytokine suppressive anti- inflammatory drug binding protein, EC 2.7.11.24, MAP kinase MXI2, MAP kinase p38, MAPK14, MAX-interacting protein 2, MK14, MXI2, Mitogen-activated protein kinase 14
Rabbit
Antigen affinity chromatography
RUO
5600, 81649, 689314, 1432, 19094, 26416
-20°C
Liquid
Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Q16539, P47811, P70618, Q15759, Q9WUI1
MAPK11, MAPK14
A synthetic phosphopeptide derived from human p38 MAPK around the phosphorylation site of Thr179 and Tyr181 (E-M-TP-G-YP-V-A)
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.