Phospho-p38 MAPK (Thr180, Tyr182) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Catalog No.	Quantity
50-198-4580	100 μL

Catalog No. 50-198-4580 Supplier Bioss Supplier No. BS2210R

Description

Rabbit Polyclonal Antibody

p38 MAPK alpha (MAPK14) and p38 MAPK beta (MAPK11) are serine/threonine kinases which act as an essential component of the MAPkinase signal transduction pathway. P38 MAPK alpha and P38 MAPK beta are two of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK11 functions are mostly redundant with those of MAPK14. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets.

Specifications

• Antigen: Phospho-p38 MAPK (Thr180, Tyr182)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: MAPK11
• Gene Accession No.: P47811, P70618, Q15759, Q16539, Q9WUI1
• Gene Alias: Crk1; CSAID-binding protein; Csaids binding protein; CSBP; CSBP1; CSBP2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 11; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAP kinase p38 beta; MAPK 11; MAPK 14; MAPK11; MAPK14; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 14; Mitogen-activated protein kinase 11; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; MXI2; p38; p38 alpha; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38-2; p38a; p38alpha; p38-alpha; p38alpha Exip; P38b; p38Beta; P38BETA2; p38MAPK; PRKM11; PRKM14; PRKM15; protein kinase, mitogen activated kinase, 11, p38beta; RK; SAPK2; SAPK2A; SAPK2B; Stress-activated protein kinase 2a; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38
• Gene Symbols: MAPK11, MAPK14
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human p38 MAPK around the phosphorylation site of (Thr180/Tyr182).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1432, 19094, 26416, 5600, 689314, 81649
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG