Invitrogen™ Phospho-p47phox (Ser304) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105496

Catalog No. PIPA5105496

Description

Antibody detects endogenous levels of NCF1/p47-phox only when phosphorylated at Ser304.

p47phox (NCF1) is required, along with NCF2 and membrane bound cytochrome b558, for activation of the latent NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in the gene can result in granulomatous disease.

Specifications

• Antigen: Phospho-p47phox (Ser304)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ncf1
• Gene Alias: 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47>phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114553, 653361
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: F1M707, P14598
• Gene Symbols: Ncf1
• Immunogen: A synthesized peptide derived from human NCF1(Accession P14598), corresponding to amino acid residues around phosphorylated Ser304.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov