Phospho-p53BP1 (Ser25, Ser29) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3020R

Catalog No. 50-198-5088

Description

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Specifications

• Antigen: Phospho-p53BP1 (Ser25, Ser29)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TP53BP1
• Gene Alias: 53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; TP53BP1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 27223, 296099, 7158
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P70399, Q12888
• Gene Symbols: TP53BP1, Trp53bp1
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG