Invitrogen™ Phospho-p73 (Tyr99) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104698

Catalog No. PIPA5104698

Description

Antibody detects endogenous levels of p73 only when phosphorylated at Tyrosine 99.

P73 (TP73) participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Specifications

• Antigen: Phospho-p73 (Tyr99)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TP73
• Gene Alias: deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; Tp73; transformation related protein 73; Trp73; Tumor protein p73
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22062, 362675, 7161
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O15350, Q9JJP2
• Gene Symbols: TP73, Trp73
• Immunogen: A synthesized peptide derived from human TP73(Accession O15350), corresponding to amino acid residues around phosphorylated Tyr99.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov