Phospho-p90 RSK1 (Ser732) Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600401B30

Catalog No. 50-199-1998

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human p90 RSK1 protein phosphorylated at S732. A BLAST analysis was used to suggest cross reactivity with p90 RSK1 from human, rat, mouse, horse, bovine, and dog based on 100% homology with the immunizing sequence. Partially cross reactivity may occur against opossum and chicken based on >90% homology with the immunizing sequence. Cross reactivity with p90 RSK1 pS732 from other sources has not been determined.

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: Phospho-p90 RSK1 (Ser732)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPS6KA1
• Gene Alias: 90 kDa ribosomal protein S6 kinase 1; CLS; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; HU-2; HU-3; ISPK-1; MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1a; MAPKAP kinase 1; MAPKAP kinase 1a; MAPKAP kinase 1c; MAPKAPK-1; Mapkapk1a; Mapkapk-1a; MAPKAPK1B; MAPKAPK1C; MAPKAPK-1c; MRX19; OTTHUMP00000004114; OTTMUSP00000010160; p90Rsk; p90-RSK; p90-RSK 1; p90-RSK 2; p90Rsk1; p90-Rsk1; p90RSK2; p90-RSK2; p90-RSK3; p90S6K; pp90RSK1; pp90RSK2; pp90RSK3; Ribosomal protein S6 kinase 2 alpha; ribosomal protein S6 kinase 2 beta; ribosomal protein S6 kinase a, polypeptide 1; ribosomal protein S6 kinase A1; ribosomal protein S6 kinase A1 L homeolog; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase II alpha; ribosomal protein S6 kinase II beta; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypept
• Host Species: Rabbit
• Regulatory Status: RUO
• Gene ID (Entrez): 100057166, 20111, 487353, 533908, 6195, 81771
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: P18653, Q15418, Q63531
• Gene Symbols: RPS6KA1
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Canine, Equine, Human, Mouse, Rat
• Product Type: Antibody