Phospho-p90RSK (Ser380) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3362R

Catalog No. 50-198-5339

Description

The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonic regulation on G-protein coupled signaling (Sheffler et al., 2006).

Specifications

• Antigen: Phospho-p90RSK (Ser380)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPS6KA2
• Gene Alias: 90 kDa ribosomal protein S6 kinase 2; 90kDa; D17Wsu134e; HU-1; HU-2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1C; MAPKAPK1A; Mapkapk1c; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; OTTHUMP00000219225; OTTHUMP00000219227; OTTHUMP00000219228; p90rsk; p90-RSK 2; p90RSK2; p90-RSK3; pp90rsk; pp90RSK3; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase A2; ribosomal protein S6 kinase alpha 2; Ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase polypeptide 2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; Ribosomal S6 kinase 3; Rps6ka2; Rps6ka-rs1; RSK; RSK1; Rsk3; RSK-3; S6K-alpha; S6K-alpha 1; S6K-alpha 2; S6K-alpha2; S6K-alpha-2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6196
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q15349
• Gene Symbols: RPS6KA2
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human p90RSK around the phosphorylation site of Ser380.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG