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Invitrogen™ Phospho-Paxillin (Tyr118) Polyclonal Antibody
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Catalog No. PIPA523327
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20 μg
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Catalog No. Quantity
PIPA523327 20 μg
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Catalog No. PIPA523327 Supplier Invitrogen™ Supplier No. PA523327
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Description

Rabbit Polyclonal Antibody

Sequence homology: Opossum/Chimpanzee/Orangutan/Salmon (100%), Tetradon (85%).

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Paxillin (Tyr118)
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene PXN
Gene Accession No. P49023, P49024, Q66H76, Q8VI36
Gene Alias adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
Gene Symbols PXN, pxna
Host Species Rabbit
Immunogen A portion of human Paxillin protein containing a phosphorylated tyrosine residue at position 118.
Purification Method Antigen affinity chromatography
Quantity 20 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100353305, 19303, 360820, 395832, 399546, 486299, 5829
Target Species Human, Mouse, Rat, Canine, Rabbit, Monkey, Chicken, Frog, Zebrafish, Rhesus Macaque
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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