Phospho-Paxillin (Tyr118) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3352R

Catalog No. 50-198-5333

Description

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: Phospho-Paxillin (Tyr118)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PXN
• Gene Alias: adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; PXN; pxna; testicular tissue protein Li 134; wu:fw71f12
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5829
• Content And Storage: -20°C
• Form: Liquid

• Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P49023
• Gene Symbols: PXN
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Paxillin around the phosphorylation site of Tyr118.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG