Invitrogen™ Phospho-Paxillin (Tyr118) Recombinant Rabbit Monoclonal Antibody (1F11)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA533194

Catalog No. PIMA533194

Description

Phospho-Paxillin (Tyr118) Recombinant Monoclonal Antibody for Western Blot, ELISA

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Specifications

• Antigen: Phospho-Paxillin (Tyr118)
• Classification: Recombinant Monoclonal
• Concentration: 1.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P49023
• Gene Symbols: PXN
• Immunogen: A synthesized peptide derived from human Phospho-PXN (Y118).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 1F11
• Conjugate: Unconjugated
• Gene: PXN
• Gene Alias: adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5829
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid