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Invitrogen™ Phospho-PDE3A (Ser312) Polyclonal Antibody
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Catalog No. PIPA5106199
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100 μL
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PIPA5106199 100 μL
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Catalog No. PIPA5106199 Supplier Invitrogen™ Supplier No. PA5106199
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PDE3A only when phosphorylated at Ser312.

Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PDE3A (Ser312)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PDE3A
Gene Accession No. Q14432, Q62865, Q9Z0X4
Gene Alias A930022O17Rik; C87899; cAMP phosphodiesterase, myocardial cGMP-inhibited; CGI-PDE; CGI-PDE A; CGI-PDE-A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A; cyclic nucleotide phosphodiesterase; HTNB; PDE3A; phosphodiesterase 3A; phosphodiesterase 3A, cGMP inhibited; phosphodiesterase 3A, cGMP-inhibited; RNPDE3A
Gene Symbols PDE3A
Host Species Rabbit
Immunogen A synthesized peptide derived from human PDE3A(Accession Q14432), corresponding to amino acid residues around phosphorylated Ser312.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50678, 5139, 54611
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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