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Phospho-PDGF Receptor beta (Tyr771) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985292
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50-198-5292 100 μL
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Catalog No. 50-198-5292 Supplier Bioss Supplier No. BS3303R
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Description

Rabbit Polyclonal Antibody

PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Specifications

Antigen Phospho-PDGF Receptor beta (Tyr771)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Pdgfrb
Gene Accession No. P09619
Gene Alias AI528809; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140b; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; PDGFR1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; Platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide
Gene Symbols Pdgfrb
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human PDGFRB around the phosphorylation site of Tyr771 [SN (p-Y)MA].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5159
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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