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Phospho-PDHA1 (Ser293) Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS4036R

Catalog No. 50-198-5851


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Description

Description

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

Phospho-PDHA1 (Ser293)
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
PDHA1
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
5160
PDHA1
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P08559
BOS_26312; PDHA; PDHA1; Pdha-1; PDHAD; PDHCE1A; PDHE1-A type I; PHE1A; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase complex, E1-alpha polypeptide 1; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 component alpha subunit; Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1 subunit; pyruvate dehydrogenase E1alpha subunit
KLH conjugated synthetic phosphopeptide derived from human PDHA1 around the phosphorylation site of Ser293.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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