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Invitrogen™ Phospho-PDX1 (Ser61) Polyclonal Antibody
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Catalog No. PIPA5118708
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PIPA5118708 100 μL
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Catalog No. PIPA5118708 Supplier Invitrogen™ Supplier No. PA5118708
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PDX1 only when phosphorylated at Ser61.

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
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Specifications

Antigen Phospho-PDX1 (Ser61)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PDX1
Gene Accession No. P52945
Gene Alias DLDBP; E3BP; Glucose-sensitive factor; GSF; Idx1; IDX-1; Insulin promoter factor 1; insulin promoter factor 1, homeodomain transcription factor; insulin promotor factor 1; insulin upstream factor 1; Ipf1; IPF-1; Islet/duodenum homeobox 1; islet/duodenum homeobox-1; IUF1; IUF-1; MODY4; PAGEN1; Pancreas/duodenum homeobox protein 1; pancreatic and duodenal homeobox 1; pancreatic and duodenal homeobox gene 1; pancreatic-duodenal homeobox factor 1; PDHX; PDX1; pdx-1; somatostatin transactivating factor 1; somatostatin transcription factor 1; somatostatin-transactivating factor 1; Stf1; STF-1
Gene Symbols PDX1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PDX1(Accession P52945), corresponding to amino acid residues around phosphorylated Ser61.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3651
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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