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Invitrogen™ Phospho-PHGDH (Thr78) Polyclonal Antibody
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Catalog No. PIPA5105069
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PIPA5105069 100 μL
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Catalog No. PIPA5105069 Supplier Invitrogen™ Supplier No. PA5105069
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PHGDH only when phosphorylated at Thr78.

PHGDH gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
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Specifications

Antigen Phospho-PHGDH (Thr78)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PHGDH
Gene Accession No. O08651, O43175, Q61753
Gene Alias 2-oxoglutarate reductase; 3PGDH; 3-PGDH; 3-phosphoglycerate dehydrogenase; 3-phosphoglycerate dehyrogenase; 4930479N23; A10; D-3-phosphoglycerate dehydrogenase; epididymis secretory protein Li 113; HEL-S-113; Malate dehydrogenase; NLS; NLS1; PDG; PGAD; PGD; PGDH; PGDH3; Phgdh; PHGDHD; phosphoglycerate dehydrogenase; SERA
Gene Symbols PHGDH
Host Species Rabbit
Immunogen A synthesized peptide derived from human PHGDH(Accession O43175), corresponding to amino acid residues around phosphorylated Thr78.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 236539, 26227, 58835
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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