Phospho-Phospholamban (Ser16, Thr17) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538317

Catalog No. PIPA538317

Description

PLB is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Specifications

• Antigen: Phospho-Phospholamban (Ser16, Thr17)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLN
• Gene Alias: PLN; phospholamban; CMD1P; PLB; cardiac phospholamban; CMH18
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18821, 5350, 64672
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P26678, P61014, P61016
• Gene Symbols: PLN
• Immunogen: A synthetic phosphopeptide derived from human Phospholamban around the phosphorylation site of Ser16 and Thr17 (R-A-SP-TP-I-E)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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