Invitrogen™ Phospho-PIKFYVE (Ser307) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538808

Catalog No. PIPA538808

Description

Phospho-PIKFYVE (Ser307) Polyclonal Antibody for ICC/IF, IHC (P)

PIKFYVE belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. The content of phosphatidylinositol 3,5-bisphosphateP2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. PIKFYVE is the PtdIns(3,5)P2-producing component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PIKFYVE activator VAC14 and the PtdIns(3,5)P2 phosphatase FIG4. In addition to its phosphoinositide 5-kinase activity, PIKFYVE also has protein kinase activity. For a review, see Shisheva.

Specifications

• Antigen: Phospho-PIKFYVE (Ser307)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PIKFYVE
• Gene Alias: 1-phosphatidylinositol 3-phosphate 5-kinase; 1-phosphatidylinositol-3-phosphate 5-kinase; 5230400C17Rik; CFD; epididymis luminal protein 37; FAB1; FYVE finger-containing phosphoinositide kinase; HEL37; Kiaa0981; p235; Phosphatidylinositol 3-phosphate 5-kinase; Phosphatidylinositol 3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate 5-kinase type III; phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III; phosphatidylinositol-4-phosphate 5-kinase, type III; phosphoinositide kinase, FYVE finger containing; phosphoinositide kinase, FYVE-type zinc finger containing; PIKfyve; Pip5k; PIP5K3; Pipk5k3; PipkIII; PIPkin-III; PtdIns(4)P-5-kinase; type III PIP kinase; ZFYVE29; zinc finger, FYVE domain containing 29
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18711, 200576
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: Dulbecco's PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9Y2I7, Q9Z1T6
• Gene Symbols: PIKFYVE
• Immunogen: A synthetic phosphopeptide derived from human PIP5K around the phosphorylation site of Ser307 (S-A-SP-I-T).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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