Invitrogen™ Phospho-PKC zeta (Thr410) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578127

Catalog No. PIPA578127

Description

Positive Control: HeLa Predicted Reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Pig (100%), Rabbit (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.

Specifications

• Antigen: Phospho-PKC zeta (Thr410)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRKCZ
• Gene Alias: 14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; AI098070; aPKCzeta; atypical protein kinase C; C80388; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; PKC2; Pkcz; PKC-ZETA; Prkcz; protein kinase C zeta; protein kinase C zeta subspecies; protein kinase C zeta type; protein kinase C, zeta; r14-3-3; R74924; zetaPKC
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5590
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.81 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q05513
• Gene Symbols: PRKCZ
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human PKC zeta (phospho Thr410). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG