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Phospho-PKC zeta (Thr560) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989760
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50-198-9760 100 μL
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Catalog No. 50-198-9760 Supplier Bioss Supplier No. BS12690R
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Description

Rabbit Polyclonal Antibody

PKC zeta is a member of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differ among tissues and PKC family member exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca2+.

Specifications

Antigen Phospho-PKC zeta (Thr560)
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 50% glycerol and 0.03% Proclin 300; pH
Gene PRKCZ
Gene Accession No. Q05513
Gene Alias 14 - 3 - 3 - zeta isoform; 14-3-3-zetaisoform; AI098070; aPKCzeta; atypical protein kinase C; C80388; kinase nPKC-zeta; KPCZ; nPKC-zeta; nPKC-zeta PRKCZ; PKC2; Pkcz; PKC-ZETA; Prkcz; protein kinase C zeta; protein kinase C zeta subspecies; Protein kinase C zeta type; protein kinase C, zeta; r14-3-3; R74924; zetaPKC
Gene Symbols PRKCZ
Host Species Rabbit
Immunogen KLH conjugated synthesised phosphopeptide derived from human PKC zeta around the phosphorylation site of Thr560.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5590
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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