Invitrogen™ Phospho-PKMYT1 (Ser83) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537656

Catalog No. PIPA537656

Description

A suggested positive control for IHC is human breast carcinoma.

PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.

Specifications

• Antigen: Phospho-PKMYT1 (Ser83)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pkmyt1
• Gene Alias: 6230424P17; AW209059; Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase; Myt1; Myt1 kinase; Pkmyt1; pkmyt1.S; PPP1R126; protein kinase, membrane associated tyrosine/threonine 1; protein kinase, membrane associated tyrosine/threonine 1 S homeolog; protein phosphatase 1, regulatory subunit 126; RGD1305434; XELAEV_18047881mg
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9088
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q99640
• Gene Symbols: Pkmyt1
• Immunogen: Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov