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Invitrogen™ Phospho-PKMYT1 (Ser120) Polyclonal Antibody
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Catalog No. PIPA5105693
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PIPA5105693 100 μL
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Catalog No. PIPA5105693 Supplier Invitrogen™ Supplier No. PA5105693
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Myt1 only when phosphorylated at Ser120.

PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PKMYT1 (Ser120)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Pkmyt1
Gene Accession No. Q99640
Gene Alias 6230424P17; AW209059; Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase; Myt1; Myt1 kinase; Pkmyt1; pkmyt1.S; PPP1R126; protein kinase, membrane associated tyrosine/threonine 1; protein kinase, membrane associated tyrosine/threonine 1 S homeolog; protein phosphatase 1, regulatory subunit 126; RGD1305434; XELAEV_18047881mg
Gene Symbols Pkmyt1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PKMYT1(Accession Q99640), corresponding to amino acid residues around phosphorylated Ser120.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9088
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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