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Invitrogen™ Phospho-PLA2G4A (Ser505) Polyclonal Antibody
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Catalog No. PIPA517790
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100 μL
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PIPA517790 100 μL
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Catalog No. PIPA517790 Supplier Invitrogen™ Supplier No. PA517790
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with the secreted PLA2 (sPLA2) or cytosolic Ca2+ independent PLA2 (iPLA2).

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PLA2G4A (Ser505)
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 250 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene PLA2G4A
Gene Accession No. P47712, P47713, P50393
Gene Alias calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A
Gene Symbols PLA2G4A
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer505 of human cPLA2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18783, 24653, 5321
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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