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Phospho-PPAR alpha (Ser12) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985866
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50-198-5866 100 μL
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Catalog No. 50-198-5866 Supplier Bioss Supplier No. BS4055R
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Description

Rabbit Polyclonal Antibody

Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPAR′s). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPAR′s are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPAR′s can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements. PPAR, like several other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha.

Specifications

Antigen Phospho-PPAR alpha (Ser12)
Applications ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PPARA
Gene Accession No. Q07869
Gene Alias 4933429D07Rik; AW742785; BOS_6232; hPPAR; MGC2237; MGC2452; NR1C1; Nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor, alpha; peroxisome proliferator activated receptor alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; Peroxisome proliferator-activated receptor alpha; Ppar; PPAR ALPHA; PPARA; PPARalpha; PPAR-alpha; proliferator-activated receptor alpha
Gene Symbols PPARA
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human PPAR alpha around the phosphorylation site of ser12.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5465
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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