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Invitrogen™ Phospho-PPIG (Ser376) Polyclonal Antibody
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Catalog No. PIPA5105205
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100 μL
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PIPA5105205 100 μL
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Catalog No. PIPA5105205 Supplier Invitrogen™ Supplier No. PA5105205
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PPIG only when phosphorylated at Ser376.

Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PPIG (Ser376)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PPIG
Gene Accession No. A2AR02, O55035, Q13427
Gene Alias AU019516; AU022200; B230312B02Rik; CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; CYP; Matrin cyclophilin; matrin cyclophilin (matrin-cyp); matrin-cyp; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidylprolyl isomerase G; peptidyl-prolyl isomerase G; peptidylprolyl isomerase G (cyclophilin G); peptidyl-prolyl isomerase G (cyclophilin G); PPIase G; PPIG; Rotamase G; SCAF10; SR-cyclophilin; SRCyp; SR-cyp; SR-related CTD-associated factor 10
Gene Symbols PPIG
Host Species Rabbit
Immunogen A synthesized peptide derived from human PPIG(Accession Q13427), corresponding to amino acid residues around phosphorylated Ser376.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 228005, 83624, 9360
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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