Invitrogen™ Phospho-PPP1R12A/PPP1R12B/PPP1R12C (Thr696) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121344

Catalog No. PIPA5121344

Description

Positive test controls include: Jurkat. Immunogen sequence: RSTQG.

Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. [NCBI].

Specifications

• Antigen: Phospho-PPP1R12A/PPP1R12B/PPP1R12C (Thr696)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP1R12A
• Gene Symbols: PPP1R12A, PPP1R12B, PPP1R12C
• Immunogen: A synthetic phosphorylated peptide around T696 of human PPP1R12A/PPP1R12B/PPP1R12CPPP1R12A (NP_0024711).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 0.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O14974, O60237, Q9BZL4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4659, 4660, 54776
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov