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Invitrogen™ Phospho-PRAK (Ser93) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA512621
Description
Phospho-PRAK (Ser93) Polyclonal Antibody for Western Blot, IHC (P)
MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.
Specifications
Phospho-PRAK (Ser93) | |
Polyclonal | |
Unconjugated | |
MAPKAPK5 | |
MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK | |
Rabbit | |
Antigen Affinity Chromatography, Protein A | |
RUO | |
17165, 8550 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
O54992, Q8IW41 | |
MAPKAPK5 | |
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S93 of human MAPKAPK5. | |
400 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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