Invitrogen™ Phospho-PRC1 (Thr470) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564766

Catalog No. PIPA564766

Description

Phospho-PRC1 (Thr470) Polyclonal Antibody detects endogenous levels of PRC1 only when phosphorylated at Thr470.

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.

Specifications

• Antigen: Phospho-PRC1 (Thr470)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRC1
• Gene Alias: anaphase spindle elongation 1 homolog; ASE1; carboxypeptidase C PRC1; Carboxypeptidase Y; Carboxypeptidase YSCY; CPD-Y; CPY1; D7Ertd348e; LBC1; MGC1671; MGC3669; prc1; protein regulating cytokinesis 1; protein regulator of cytokinesis 1; YMR297W
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 233406, 9055
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O43663, Q99K43
• Gene Symbols: PRC1
• Immunogen: A synthesized peptide derived from human PRC1 (Phospho-Thr470).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG