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Invitrogen™ Phospho-PRC1 (Thr470) Polyclonal Antibody
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Catalog No. PIPA5106103
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100 μL
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PIPA5106103 100 μL
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Catalog No. PIPA5106103 Supplier Invitrogen™ Supplier No. PA5106103
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PRC1 only when phosphorylated at Thr470.

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PRC1 (Thr470)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PRC1
Gene Accession No. O43663, Q99K43
Gene Alias anaphase spindle elongation 1 homolog; ASE1; carboxypeptidase C PRC1; Carboxypeptidase Y; Carboxypeptidase YSCY; CPD-Y; CPY1; D7Ertd348e; LBC1; MGC1671; MGC3669; prc1; protein regulating cytokinesis 1; protein regulator of cytokinesis 1; YMR297W
Gene Symbols PRC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PRC1(Accession O43663), corresponding to amino acid residues around phosphorylated Thr470.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 233406, 9055
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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