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Phospho-PRKCA (Ser657, Tyr658) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
SDP

Catalog No. 501986656
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50-198-6656 100 μL
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Catalog No. 50-198-6656 Supplier Bioss Supplier No. BS5573R
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Description

Rabbit Polyclonal Antibody

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Specifications

Antigen Phospho-PRKCA (Ser657, Tyr658)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PRKCA
Gene Accession No. P05696, P17252, P20444
Gene Alias AAG6; aging-associated gene 6; AI875142; BOS_19579; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; PKCA; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; PRKCA; prkcaa; protein kinase C alpha; Protein kinase C alpha type; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; protein kinase, C alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045)
Gene Symbols PRKCA
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Ser657+Tyr658.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18750, 24680, 5578
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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