Phospho-PRKCA (Ser657, Tyr658) Rabbit anti-Human|Mouse|Rat, Polyclonal, Bioss 

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS5573R

Catalog No. 50-198-6656

Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Specifications

• Antigen: Phospho-PRKCA (Ser657, Tyr658)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: PRKCA
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 18750, 24680, 5578

• Gene Symbol: PRKCA
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P05696, P17252, P20444
• Gene Alias: AAG6; aging-associated gene 6; AI875142; BOS_19579; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; PKCA; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; PRKCA; prkcaa; protein kinase C alpha; Protein kinase C alpha type; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; protein kinase, C alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045)
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Ser657+Tyr658.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Mouse, Rat