Invitrogen™ Phospho-RAB29 (Ser72) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114630

Catalog No. PIPA5114630

Description

Antibody detects endogenous levels of RAB7L1 only when phosphorylated at Rab29.

Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection. {ECO:0000269; PubMed:22042847, ECO:0000269; PubMed:24788816}.

Specifications

• Antigen: Phospho-RAB29 (Ser72)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB29
• Gene Alias: RAB29; RAB29, member RAS oncogene family; RAB7, member RAS oncogene family-like 1; RAB7L; RAB7L1; Rab-7-like protein 1; Ras-related GTP-binding protein Rab29; ras-related protein Rab-29; Ras-related protein Rab-7L1
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171122, 226422, 8934
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O14966, Q63481, Q91YQ1
• Gene Symbols: RAB29
• Immunogen: A synthesized peptide derived from human Rab7L1 around the phosphorylation site of Rab29.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov