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Invitrogen™ Phospho-RAD17 (Ser359) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5105434
Description
Antibody detects endogenous levels of RAD17 only when phosphorylated at Ser359.
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Specifications
Phospho-RAD17 (Ser359) | |
Polyclonal | |
Unconjugated | |
Rad17 | |
CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W | |
Rabbit | |
Sequential Chromatography | |
RUO | |
19356, 310034, 5884 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
O75943, Q6NXW6 | |
Rad17 | |
A synthesized peptide derived from human RAD17(Accession O75943), corresponding to amino acid residues around phosphorylated Ser359. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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