Phospho-Rad17 (Ser645) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3370R

Catalog No. 50-198-5347

Description

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

Specifications

• Antigen: Phospho-Rad17 (Ser645)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rad17
• Gene Alias: CCYC; cell cycle checkpoint protein (RAD17); Cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; Rad17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5884
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: O75943
• Gene Symbols: Rad17
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Rad17 around the phosphorylation site of Ser645.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG