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Phospho-RAD17 (Ser656) Recombinant Polyclonal Antibody (1HCLC), Invitrogen™

Catalog No. PI711120
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100 μg
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Catalog No. Quantity
PI711120 100 μg
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Catalog No. PI711120 Supplier Thermo Scientific Supplier No. 711120

Description

Rabbit Recombinant Polyclonal Antibody

This antibody is predicted to react with Monkey, Sheep and Bovine Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RAD17 (Ser656)
Applications Western Blot
Classification Recombinant Polyclonal
Clone 1HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Rad17
Gene Accession No. O75943
Gene Alias CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W
Gene Symbols Rad17
Host Species Rabbit
Immunogen Peptide corresponding to Human RAD17 (aa 653-660)
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5884
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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