Phospho-RAD51 (Thr309) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS5677R

Catalog No. 50-198-6716

Description

RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.

Specifications

• Antigen: Phospho-RAD51 (Thr309)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rad51
• Gene Alias: AV304093; BOS_10731; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; FANCR; homolog to S.cerevisiae; HRAD51; HsRAD51; HsT16930; MRMV2; MUT5; Rad51; RAD51 homolog; RAD51 homolog (RecA homolog, E. coli); RAD51 homolog (S. cerevisiae); RAD51 homolog A; RAD51 recombinase; Rad51a; RECA; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; wu:fb38e12; YER095W; zgc:77754
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5888
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q06609
• Gene Symbols: Rad51
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Thr309 [GE (p-T)RI].
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG