Invitrogen™ Phospho-Raptor (Ser863) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106203

Catalog No. PIPA5106203

Description

Antibody detects endogenous levels of Raptor only when phosphorylated at Ser863.

Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.

Specifications

• Antigen: Phospho-Raptor (Ser863)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPTOR
• Gene Alias: 4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Rap; RAPTOR; regulatory associated protein of MTOR complex 1; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RGD1311784; RPTOR
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 287871, 57521, 74370
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8K4Q0, Q8N122
• Gene Symbols: RPTOR
• Immunogen: A synthesized peptide derived from human RPTOR(Accession Q8N122), corresponding to amino acid residues around phosphorylated Ser863.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG