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Invitrogen™ Phospho-RASGRF1 (Ser927) Polyclonal Antibody
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Catalog No. PIPA5105157
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100 μL
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PIPA5105157 100 μL
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Catalog No. PIPA5105157 Supplier Invitrogen™ Supplier No. PA5105157
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Ras-GRF1 only when phosphorylated at Ser927.

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RASGRF1 (Ser927)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RASGRF1
Gene Accession No. P27671, P28818, Q13972
Gene Alias AI844718; ASPP1; Cdc25; CDC25L; CDC25Mm; Gnrp; GRF1; GRF55; Grfbeta; guanine nucleotide exchange factor; guanine nucleotide-releasing factor 1; guanine nucleotide-releasing factor, 55 kD; guanine nucleotide-releasing protein; H-GRF55; KIAA0771; P140 Ras-GRF; p190; P190-A; p190RhoGEF; PP13187; PPP1R13B; Ras guanine release factor beta; Ras protein specific guanine nucleotide releasing factor 1; RAS protein-specific guanine nucleotide-releasing factor 1; Rasgrf1; ras-GRF1; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific guanine nucleotide-releasing factor, CDC25 homolog; ras-specific nucleotide exchange factor CDC25
Gene Symbols RASGRF1
Host Species Rabbit
Immunogen A synthesized peptide derived from human RASGRF1(Accession Q13972), corresponding to amino acid residues around phosphorylated Ser927.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192213, 19417, 5923
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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