Phospho-Rb/P105 RB (Ser807, Ser811) Rabbit anti-Human|Mouse|Rat, Polyclonal, Bioss 

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS3380R

Catalog No. 50-198-5355

Description

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Specifications

• Antigen: Phospho-Rb/P105 RB (Ser807, Ser811)
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: RB1
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 19645, 24708, 5925

• Gene Symbol: RB1
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P06400, P13405, P33568
• Gene Alias: Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human P105 RB around the phosphorylation site of Ser807/Ser811.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Mouse, Rat