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Invitrogen™ Phospho-Rb (Ser807) Recombinant Rabbit Monoclonal Antibody (1T3E10)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA542953
This item is not returnable.
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Description
The target is usually found in the following locations: Nucleus. Immunogen sequence: YISPL.
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Specifications
Phospho-Rb (Ser807) | |
Recombinant Monoclonal | |
0.65 mg/mL | |
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P06400, P13405, P33568 | |
RB1 | |
A synthetic phosphorylated peptide around S807 of human RB (P06400). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
ELISA, Western Blot | |
1T3E10 | |
Unconjugated | |
RB1 | |
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein | |
Rabbit | |
Affinity chromatography | |
RUO | |
19645, 24708, 5925 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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