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Invitrogen™ Phospho-Rb (Ser807, Ser811) Recombinant Rabbit Monoclonal Antibody (RbS807S811-D9), APC, Invitrogen™

Catalog No. PIMA537246
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100 Tests
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PIMA537246 10 Tests
PIMA536944 100 Tests
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Catalog No. PIMA537246 Supplier Invitrogen™ Supplier No. MA537246
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Rabbit Recombinant Monoclonal Antibody

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Rb (Ser807, Ser811)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone RbS807S811-D9
Conjugate APC
Formulation PBS with 0.20% BSA and 0.09% sodium azide
Gene RB1
Gene Accession No. P06400, P13405
Gene Alias Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein
Gene Symbols RB1
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Ser807/811 of human phospho-Rb.
Purification Method Protein A/G
Quantity 10 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19645, 5925
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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