Phospho-Ret (Tyr1062) Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS3385R

Catalog No. 50-198-5358

Description

RET is a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases which are cell-surface molecules that transduce signals for cell growth and differentiation. RET plays a crucial role in neural crest development, can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.

Specifications

• Antigen: Phospho-Ret (Tyr1062)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RET
• Gene Alias: Cadherin family member 12; cadherin-related family member 16; CDHF12; CDHR16; CG1061; CG14396; CG14396 gene product from transcript CG14396-RA; CG14396-PA; CG14396-PB; CG14396-PC; c-Ret; CUX1/RET fusion; Dmel\CG14396; Dmel_CG14396; DmHD-59; DmRet; DRET; D-ret; EC 2.7.10.1; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment; HD-59; HSCR1; hydroxyaryl-protein kinase; kinase Ret; MEN2; MEN2A; MEN2B; MTC1; OTTHUMP00000216967; Proto-oncogene c-Ret; Proto-oncogene tyrosine-protein kinase receptor Ret; PTC; rearranged during transfection; receptor tyrosine kinase; RET; Ret gene for receptor tyrosin; Ret oncogene; ret proto-oncogene; ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease); Ret proto-oncogene (multiple endocrine neoplasia MEN2A MEN2B and medullary thyroid carcinoma 1 Hirschsprung disease); RET receptor tyrosine kinase; RET transforming sequence; RET51; RET9; RET-ELE1; Reto; Ret-PA; Ret-PB; Ret-PC; Soluble RET kinase fragment
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5979
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P07949
• Gene Symbols: RET
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human Ret around the phosphorylation site of Tyr1062.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG