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Invitrogen™ Phospho-ROCK2 (Ser1379) Polyclonal Antibody
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Catalog No. PIPA5105416
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PIPA5105416 100 μL
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Catalog No. PIPA5105416 Supplier Invitrogen™ Supplier No. PA5105416
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ROCK2 only when phosphorylated at Ser1379.

ROCK2, the predominant ROCK isoform in skeletal muscle, is an important regulator downstream of Rho GTPases. ROCK2 regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ROCK2 (Ser1379)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ROCK2
Gene Accession No. O75116, P70336, Q62868
Gene Alias B230113H15Rik; KIAA0619; mKIAA0619; p150 ROK-alpha; p164 ROCK-2; Rho associated coiled-coil containing protein kinase 2; Rho kinase 2; RhoA - binding serine/threosine kinase alpha (ROK - alpha); rhoA-binding kinase 2; Rho-associated coiled-coil containing protein kinase 2; Rho-associated coiled-coil forming kinage 2; Rho-associated coiled-coil forming kinase 2; rho-associated protein kinase 2; Rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; Rho-kinase; ROCK II; Rock2; Rock2m; rockii; ROCK-II; ROK; ROKalpha
Gene Symbols ROCK2
Host Species Rabbit
Immunogen A synthesized peptide derived from human ROCK2(Accession O75116), corresponding to amino acid residues around phosphorylated Ser1379.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19878, 25537, 9475
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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