Invitrogen™ Phospho-RSK2 (Thr577) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105587

Catalog No. PIPA5105587

Description

Antibody detects endogenous levels of RSK2 only when phosphorylated at Thr577.

RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).

Specifications

• Antigen: Phospho-RSK2 (Thr577)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPS6KA3
• Gene Alias: 90 kDa ribosomal protein S6 kinase 3; C130006E23; CLS; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK1B; MAPKAPK-1b; MPK-9; MRX19; p90-RSK 3; p90-RSK2; p90RSK3; pp90RSK2; RGD1563860; ribosomal protein S6 kinase 2; ribosomal protein S6 kinase A3; ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; Rps6ka3; Rps6ka-rs1; RSK; Rsk2; RSK-2; S6K-alpha3; S6K-alpha-3
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 110651, 501560, 6197
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P18654, P51812
• Gene Symbols: RPS6KA3
• Immunogen: A synthesized peptide derived from human RPS6KA3(Accession P51812), corresponding to amino acid residues around phosphorylated Thr577.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov