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Invitrogen™ Phospho-RSK2 (Thr577) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105587

Catalog No. PIPA5105587


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Description

Description

Antibody detects endogenous levels of RSK2 only when phosphorylated at Thr577.

RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-RSK2 (Thr577)
Polyclonal
Unconjugated
RPS6KA3
90 kDa ribosomal protein S6 kinase 3; C130006E23; CLS; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK1B; MAPKAPK-1b; MPK-9; MRX19; p90-RSK 3; p90-RSK2; p90RSK3; pp90RSK2; RGD1563860; ribosomal protein S6 kinase 2; ribosomal protein S6 kinase A3; ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; Rps6ka3; Rps6ka-rs1; RSK; Rsk2; RSK-2; S6K-alpha3; S6K-alpha-3
Rabbit
Sequential Chromatography
RUO
110651, 501560, 6197
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P18654, P51812
RPS6KA3
A synthesized peptide derived from human RPS6KA3(Accession P51812), corresponding to amino acid residues around phosphorylated Thr577.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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