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Invitrogen™ Phospho-RSK2 (Thr577) Polyclonal Antibody
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Catalog No. PIPA5105587
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100 μL
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PIPA5105587 100 μL
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Catalog No. PIPA5105587 Supplier Invitrogen™ Supplier No. PA5105587
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of RSK2 only when phosphorylated at Thr577.

RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RSK2 (Thr577)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RPS6KA3
Gene Accession No. P18654, P51812
Gene Alias 90 kDa ribosomal protein S6 kinase 3; C130006E23; CLS; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK1B; MAPKAPK-1b; MPK-9; MRX19; p90-RSK 3; p90-RSK2; p90RSK3; pp90RSK2; RGD1563860; ribosomal protein S6 kinase 2; ribosomal protein S6 kinase A3; ribosomal protein S6 kinase alpha-3; ribosomal protein S6 kinase polypeptide 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; Rps6ka3; Rps6ka-rs1; RSK; Rsk2; RSK-2; S6K-alpha3; S6K-alpha-3
Gene Symbols RPS6KA3
Host Species Rabbit
Immunogen A synthesized peptide derived from human RPS6KA3(Accession P51812), corresponding to amino acid residues around phosphorylated Thr577.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110651, 501560, 6197
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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