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Invitrogen™ Phospho-RSK3 (Ser360) Polyclonal Antibody
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Catalog No. PIPA5105917
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100 μL
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PIPA5105917 100 μL
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Catalog No. PIPA5105917 Supplier Invitrogen™ Supplier No. PA5105917
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of RSK3 only when phosphorylated at Ser360.

RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It is believed that RPS6KA2 is a signal-transducing intermediate in the cellular response to several growth factors. It is found in many tissues, but in higher levels in lung and skeletal muscle. The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits and may have a tonic regulation on G-protein coupled signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RSK3 (Ser360)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RPS6KA2
Gene Accession No. Q15349, Q9WUT3
Gene Alias 90 kDa ribosomal protein S6 kinase 2; 90kDa; D17Wsu134e; HU-2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1C; MAPKAPK1C; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; p90rsk; p90-RSK 2; p90RSK2; p90-RSK3; pp90rsk; pp90RSK3; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase A2; ribosomal protein S6 kinase alpha 2; ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase polypeptide 2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; ribosomal protein S6 kinase, polypeptide 2; ribosomal S6 kinase 3; Rps6ka2; Rps6ka-rs1; RSK; Rsk3; RSK-3; S6K-alpha; S6K-alpha 2; S6K-alpha2; S6K-alpha-2
Gene Symbols RPS6KA2
Host Species Rabbit
Immunogen A synthesized peptide derived from human RPS6KA2(Accession Q15349), corresponding to amino acid residues around phosphorylated Ser360.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117269, 20112, 6196
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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